Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
نویسندگان
چکیده
منابع مشابه
International Funding for Malaria Control in Relation to Populations at Risk of Stable Plasmodium falciparum Transmission
BACKGROUND The international financing of malaria control has increased significantly in the last ten years in parallel with calls to halve the malaria burden by the year 2015. The allocation of funds to countries should reflect the size of the populations at risk of infection, disease, and death. To examine this relationship, we compare an audit of international commitments with an objective a...
متن کاملThe Use of Crude Plasmodium falciparum Antigens for Comparison of Antibody Responses in Patients with Mild Malaria vs. Cerebral Malaria
Background: Cerebral malaria (CM) is one of the major causes of death in African populations infected with Plasmodium falciparum. Only 1% of infected subjects develop CM. The reasons for these differences are not fully understood, but it is likely that the host humoral response against blood-stage antigens plays a role in protection from malaria, although the precise targets and mechanisms medi...
متن کاملMicro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa.
Background: The first models of malaria transmission assumed a completely mixed and homogeneous population of parasites. Recent models include spatial heterogeneity and variably mixed populations. However, there are few empiric estimates of parasite mixing with which to parametize such models. Methods: Here we genotype 276 single nucleotide polymorphisms (SNPs) in 5199 P. falciparum isolates f...
متن کاملMicro - epidemiological structuring of Plasmodium parasite populations in regions with varying falciparum transmission intensities in Africa
The first models of malaria transmission assumed a completely Background: mixed and homogeneous population of parasites. Recent models include spatial heterogeneity and variably mixed populations. However, there are few empiric estimates of parasite mixing with which to parametize such models. : Here we genotype 276 single nucleotide polymorphisms (SNPs) in Methods 5199 isolates from two Kenya...
متن کاملMicro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission
The first models of malaria transmission assumed a completely Background: mixed and homogeneous population of parasites. Recent models include spatial heterogeneity and variably mixed populations. However, there are few empiric estimates of parasite mixing with which to parametize such models. : Here we genotype 276 single nucleotide polymorphisms (SNPs) in Methods 5199 isolates from two Kenya...
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ژورنال
عنوان ژورنال: International Journal of Biotechnology
سال: 2007
ISSN: 0963-6048,1741-5020
DOI: 10.1504/ijbt.2007.014249